由Phytophthora nicotianae的EPIC1的晶体结构揭示了两个不同的域互换二元结构

Gwan Hee Lee1, Yong Jun Kang1, Hyo Been Jin1

  • 1College of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea; Department of Global Innovative Drugs, Graduate School of Chung-Ang University, Seoul, 06974, Republic of Korea.

概括

植物病原体EPIC1,一种类似囊类的抑制剂,形成独特的二硫化物结合二元体. 通过高分辨率晶体学揭示的这种新型结构可能会在宿主相互作用中增强其稳定性和特异性.