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Updated: Sep 9, 2025

Application and Methodology of the Non-destructive 19F Time-domain NMR Technique to Measure the Content in Fluorine-containing Drug Products
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用时域NMR测量T2放松计量无形固体分散中的活性药物成分的定量评价

Tsunenobu Katsumata1, Hiromu Taguchi2, Yusuke Minamino2

  • 1Formulation Development Department, Development & Planning Division, Nichi-Iko Pharmaceutical Co., Ltd., 205-1 Shimoumezawa, Namerikawa, Toyama, 936-0857, Japan.

Journal of pharmaceutical sciences
|August 28, 2025
PubMed
概括

这项研究引入了时间域NMR T2放松计,作为一种新的方法来量化固体分散剂 (SD) 中的活性药物成分 (API) 水晶性. 该技术准确地测量了API晶度,为传统方法提供了有价值的替代方案.

关键词:
结晶性量化评价固体分散T(2) 放松计时间域NMR转化情况

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