华法林诱导的舌下和喉出血症患者的呼吸道阻塞
Mohamed Darwish1, Fathiya Al Nagbi1, Hamed Aljanaahi1
1Department of Emergency Medicine, Tawam Hospital, Al Ain, Abu Dhabi, UAE.
BMJ case reports
|August 28, 2025
概括
华法林治疗可能导致罕见的气道血瘤,导致阻塞. 紧急气管切除术成功治疗了一个患有超治疗性国际正常比率的患者的喉下血瘤.
科学领域:
- 医学
- 血液学
- 耳鼻喉科
背景情况:
- 华法林治疗通常会导致胃肠道,尿道和内出血.
- 呼吸道血瘤是华法林治疗的罕见但严重并发症,特别是在超治疗性国际规范化比率 (INR) 时.
- 消化不良,流口水,发声不良和说话不良等症状表明呼吸道可能受影响.
研究的目的:
- 在接受华法林治疗的患者中呈现出导致气道阻塞的下喉血瘤.
- 讨论呼吸道血瘤的诊断和治疗策略.
- 强调多学科团队参与应急呼吸道管理的重要性.
主要方法:
- 一个50多岁的男性患者的病例报告.
- 对目前难以管理呼吸道的指导方针进行审查.
- 讨论保守与最终的气道管理选项.
主要成果:
- 患者出现了暗示呼吸道受损的症状.
- 我们成功地进行了急救气管切割,
- 患者的呼吸道也恢复了.
结论:
- 虽然很少见,但它们是华法林治疗的关键并发症,需要迅速识别.
- 早期的怀疑和干预,包括气管切除术等确切的呼吸道管理,对于患者的生存至关重要.
- 一个多学科的方法对于即将发生的气道阻塞的有效管理至关重要.
相关概念视频
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
1.3K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
1.3K
Venous Thrombosis III: Interprofessional Care
22
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
22
Anticoagulant Drugs: Low-Molecular-Weight Heparins
889
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
889
Disorders of Hemostasis
1.2K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
1.2K
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
44
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
44
Tonsillitis II: Management
174
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
174


