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Updated: Sep 9, 2025

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核酸修饰对mRNA翻译的影响:选择正确的修饰

Mouldy Sioud1

  • 1Division of Cancer Medicine, Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway. mosioud@medisin.uio.no.

Methods in molecular biology (Clifton, N.J.)
|August 28, 2025
PubMed
概括

传递 RNA (mRNA) 疗法的进步利用修饰的核酸来增强稳定性和减少免疫反应. 优化修改类型和位置对于有效的mRNA翻译和治疗开发至关重要.

关键词:
化学修饰在体外转录改性核酸N1 甲基伪乌里丁伪乌里丁翻译

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