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Updated: Sep 8, 2025

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增强癌症疫苗的有效性:在树突细胞中基于siRNA的免疫抑制因子的调节

Stein Sæbøe-Larssen1, Mouldy Sioud2

  • 1Section for Cellular Therapy, Department of Oncology, Oslo University Hospital Radiumhospitalet, Oslo, Norway.

Methods in molecular biology (Clifton, N.J.)
|August 28, 2025
PubMed
概括

新的树突细胞 (DC) 癌症疫苗利用RNA干扰来抑制像胺二氧化酶1 (IDO1) 这样的免疫抑制因素. 这些先进的DC疫苗有效地刺激T细胞,并显示患者的抗瘤活性.

关键词:
检查点接收器免疫抑制印度莱胺2,3-二氧化酶小干扰RNAs

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