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Updated: May 13, 2026

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基于4D快速DIA L-乳酸定量基因组学的乳化 (LA) 风险特征的构建

Fan Zou1, Yongchen Jin1, Ziteng Zhang1

  • 1Department of Urology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100176, China.

Journal of translational medicine
|August 28, 2025
PubMed
概括

乳化是前列腺癌进展的关键. 一个新的LA风险模型有效预测患者的预后,KCNMA1被确定为抑制瘤生长的潜在治疗标.

关键词:
生物信息学KCNMA1 其他乳化MAPK信号通道预测模型

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Dipeptidyl Peptidase 4 Inhibitors01:23

Dipeptidyl Peptidase 4 Inhibitors

Dipeptidyl peptidase 4 (DPP-4) is a serine protease widely distributed in the body. It's involved in the inactivation of GLP-1 and GIP hormones, which are crucial for insulin regulation. DPP-4 inhibitors, such as sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), alogliptin (Nesina), and vildagliptin (Galvus), help increase the proportion of active GLP-1, enhancing insulin secretion. These inhibitors work by competitively binding to DPP-4. This binding causes a significant...