Jove
Visualize
联系我们

相关概念视频

Tumor Immunotherapy01:27

Tumor Immunotherapy

659
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
659
Cancer Vaccines01:30

Cancer Vaccines

509
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
509
T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

4.5K
T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
4.5K
Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

1.9K
Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
1.9K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

DNGR-1 regulates proliferation and migration of bone marrow dendritic cell progenitors.

The Journal of experimental medicine·2025
Same journal

Impact of Multimodal Oncological Therapy on Survival and Local Control in Unresectable Perihilar Cholangiocarcinoma.

Cancer medicine·2026
Same journal

Microenvironmental Cues That Regulate Cancer Cell Dormancy in Estrogen-Receptor Positive and Triple-Negative Breast Cancer Cell Lines.

Cancer medicine·2026
Same journal

The Association Between Number of Hospital Advanced Practice Providers and Surgical Morbidity.

Cancer medicine·2026
Same journal

Feasibility Study of Combined Systemic Therapy and Carbon-Ion Radiotherapy for Hepatocellular Carcinoma Patients.

Cancer medicine·2026
Same journal

A Prognostic Risk Model Based on Immune Genes in Thyroid Cancer and Its Correlation With Tumor-Associated Immune Cell Infiltration Abundance.

Cancer medicine·2026
Same journal

Robotic Partial Nephrectomy: Different Surgical Approaches for Different Locations.

Cancer medicine·2026
查看所有相关文章
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Sep 9, 2025

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
08:40

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

Published on: August 1, 2013

18.4K

在癌症中增强树突细胞功能

Evangelos Giampazolias1

  • 1Cancer Immunosurveillance Group, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, UK.

Cancer medicine
|August 29, 2025
PubMed
概括
此摘要是机器生成的。

树突细胞 (DCs) 对于T细胞免疫力至关重要. 了解DC功能可以改善基于T细胞的癌症免疫疗法,包括免疫检查点阻断.

关键词:
T细胞启动激活方式抗原呈现方式癌症免疫力树突细胞免疫疗法

更多相关视频

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
11:48

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes

Published on: May 31, 2018

11.6K
Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
09:15

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

3.5K

相关实验视频

Last Updated: Sep 9, 2025

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
08:40

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

Published on: August 1, 2013

18.4K
Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
11:48

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes

Published on: May 31, 2018

11.6K
Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
09:15

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

3.5K

科学领域:

  • 免疫学
  • 癌症学
  • 细胞生物学

背景情况:

  • 树突细胞 (DCs) 是关键的免疫细胞,启动T细胞反应.
  • 对抗癌症免疫力和免疫疗法的有效性起着重要作用.
  • 通过各种受体检测病原体和组织损伤,影响抗瘤免疫力.

研究的目的:

  • 审查树突细胞生物学的基本原则.
  • 突出控制癌症T细胞反应的DC特征.
  • 探索DC功能如何用于新型癌症免疫疗法.

主要方法:

  • 关于树突细胞生物学和癌症免疫学的现有科学文献的审查.
  • 在抗瘤免疫的背景下分析DC的功能特征.
  • 探索DC功能与T细胞介导疗法之间的联系,包括免疫检查点阻塞.

主要成果:

  • 树突细胞对于指导T细胞免疫力对抗癌症至关重要.
  • 电流受体和传感能力有助于抗瘤CD8+T细胞的诱导.
  • DC功能与免疫检查点阻塞治疗的增强反应有关.

结论:

  • 状细胞生物学提供了关于癌症免疫力的关键见解.
  • 开发更好的癌症免疫疗法具有前景.
  • 进一步了解DC可以优化T细胞治疗癌症患者.