相关实验视频

Updated: May 3, 2026

Experimental Approach to Examine Leptin Signaling in the Carotid Bodies and its Effects on Control of Breathing
05:45

Experimental Approach to Examine Leptin Signaling in the Carotid Bodies and its Effects on Control of Breathing

Published on: October 25, 2019

6.0K

Pro64Ser瘦素突变体的结构和功能表征:对先天性瘦素缺乏症的影响

Bao Quoc Ngo1, Outi Lampela2, André H Juffer2

  • 1Faculty of Biochemistry and Molecular Medicine, University of Oulu, PO Box 5400, 90014, Oulu, Finland.

Biophysical journal
|August 29, 2025
PubMed
概括

由于LEP基因突变,先天性瘦素缺乏导致儿童肥胖. 通过改变蛋白循环动态,Pro64Ser突变破坏了瘦素信号传递,防止了LepR相互作用和下游效应.

更多相关视频

Label-Free Imaging of Lipid Storage Dynamics in Caenorhabditis elegans using Stimulated Raman Scattering Microscopy10:59

Label-Free Imaging of Lipid Storage Dynamics in Caenorhabditis elegans using Stimulated Raman Scattering Microscopy

Published on: May 28, 2021

4.3K
Author Spotlight: Hypothalamic Neural Mechanism Insights09:29

Author Spotlight: Hypothalamic Neural Mechanism Insights

Published on: August 4, 2023

3.9K

相关概念视频

Lethal Alleles02:41

Lethal Alleles

Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
11.3K