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在石墨烯氧化物上的电聚合聚 (刚果红色):一种用于电化学感应的新型平台

Çağrı Ceylan Koçak¹, Şükriye Karabiberoğlu²

¹Bergama Vocational School, Dokuz Eylul University, 35700, Izmir, Turkey.

Analytical methods : advancing methods and applications

|August 29, 2025

概括

一个新的复合电极 (PCR/GO/GCE) 增强了阿西克洛维尔的检测. 这种基于氧化石墨烯的传感器提供了一种敏感和选择性的方法来分析药物样本中的抗病毒药物.

科学领域:

电化学
材料科学
分析化学

背景情况:

艾西克洛维尔 (ACV) 是一种重要的抗病毒药物.
敏感和选择性的检测方法对于药物分析至关重要.
石墨烯氧化物和刚果红色具有有前途的电化学特性.

研究的目的:

开发一种敏感和选择性的电化学传感器来检测阿西克洛维尔.
描述一种新的复合电极材料.
在真实的药物样本中评估传感器的性能.

主要方法:

在石墨烯氧化物/玻璃碳电极上进行刚果红的电聚合 (PCR/GO/GCE).
使用扫描电子显微镜 (SEM) 和电化学阻抗光谱 (EIS) 进行表面表征.
在布里顿- 罗宾逊缓冲器中使用循环电压测量 (CV) 和差值脉冲电压测量 (DPV) 来对阿西克洛维尔进行电化学分析.

主要成果:

与裸体电极相比,PCR/GO/GCE的电流响应增加了45倍.
DPV分析显示线性检测范围为0. 01至1. 3μmol L-1和2. 2至18μmol L-1.
达到了 3.4 nmol L-1 的低检测极限.
传感器显示有选择性且稳定的反应.

结论:

开发的PCR/GO/GCE传感器对于敏感和选择性的阿西克洛维尔检测非常有效.
该传感器表现出卓越的性能和实用性,用于制药样本分析.
这种复合电极代表了抗病毒药物的电化学传感的重大进步.

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