Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

965
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
965
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

316
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
316
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

27
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
27
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

148
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
148
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

128
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
128
Gallbladder01:17

Gallbladder

896
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
896
这页已由机器翻译。其他页面可能仍然显示为英文。View in English
  1. 首页
  2. 研究领域
  3. 生物医学和临床科学
  4. 免疫学
  5. 自体免疫性
  6. 胆囊粉症往往是意想不到的,可能会对全身产生影响

胆囊粉症往往是意想不到的,可能会对全身产生影响

Catherine E Hagen1, Surendra Dasari2, Jason D Theis1

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States.

American journal of clinical pathology
|August 29, 2025

相关实验视频

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
08:56

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

Published on: February 10, 2015

52.8K
Performing and Processing FNA of Anterior Fat Pad for Amyloid
09:41

Performing and Processing FNA of Anterior Fat Pad for Amyloid

Published on: October 30, 2010

55.4K
A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia
09:12

A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia

Published on: February 3, 2023

2.6K

在PubMed 上查看摘要

概括
此摘要是机器生成的。

胆囊粉症通常是意外的诊断,胆囊经常是第一个被发现的疾病组织. 所有被研究的患者都表现出全身性干扰,强调了早期检测和治疗的必要性.

科学领域:

  • 病理学
  • 医疗诊断
  • 蛋白质组学

背景情况:

  • 氨基粉症是一种全身性疾病,其特征是错误折叠的蛋白质在细胞外沉积.
  • 胆囊参与粉样性粉症并未得到广泛认可,可能导致诊断延迟.

研究的目的:

  • 分析大量胆囊粉症病例.
  • 确定胆囊粉症的临床和形态特征.
  • 确定胆囊中粉样蛋白的类型和发病率.

主要方法:

  • 在2008年至2023年间分析的118个胆囊切除样本的回顾性审查.
  • 基于蛋白质组的技术用于粉样蛋白类型.
  • 评估了临床和形态特征.

主要成果:

  • 鉴定了六种类型的粉样蛋白,其中最常见的是粉样蛋白链和轻链粉样蛋白.
  • 在有临床信息的患者中,一半的患者被诊断出有粉症.
  • 在所有形态上审查的病例中观察到周围肌肉血管的参与.
  • 随访的所有患者都显示出全身性疾病的迹象.

结论:

  • 胆囊 Amyloidosis 经常是一个意想不到的发现,可能是系统性疾病的初始表现.
关键词:
粉症心脏病的发生胆囊切除术胆囊

相关实验视频

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
08:56

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

Published on: February 10, 2015

52.8K
Performing and Processing FNA of Anterior Fat Pad for Amyloid
09:41

Performing and Processing FNA of Anterior Fat Pad for Amyloid

Published on: October 30, 2010

55.4K
A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia
09:12

A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia

Published on: February 3, 2023

2.6K
  • 仔细检查胆囊切除样本,特别是肌周血管,至关重要.
  • 特别是在老年患者中,迅速的粉样蛋白排型可以防止诊断延迟并改善治疗.
  • 蛋白质组学
    系统性粉症