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Updated: Sep 9, 2025

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在早期类风湿关节炎中,可溶性免疫检查点分子PD1和4-1BB与CTLA-4Ig治疗反应的关联

Tilia Selldén1, Kristina Lend2, Jon Lampa3

  • 1Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

ACR open rheumatology
|August 29, 2025
PubMed
概括

在早期类风湿性关节炎患者中,可溶性编程细胞死亡-1 (sPD1) 和可溶性4-1BB (s4-1BB) 的高水平预示着阿巴特雷克萨特治疗对阿巴特雷克萨特的良好反应. 这些生物标志物与PD1+ T毛囊辅助细胞结合,显示出预测治疗缓解的潜力.

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