[心脏性痴呆症]
R G Esin1,2, E A Gorobets1, A I Mashtakova1
1Kazan Federal University, Kazan, Russia.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
|August 29, 2025
概括
心脏病显著导致脑血管疾病,如认知障碍和痴呆症. 了解这些联系对于更好的诊断和预防策略至关重要.
科学领域:
- 神经学
- 心脏病学
- 老年学
背景情况:
- 脑血管疾病的讨论往往集中在动脉上, 忽视了心脏的关键作用.
- 心脏病是大脑血管疾病的主要原因,包括认知障碍和痴呆症.
- 随意分离心血管和脑血管疾病的管理, 阻碍了全面的患者护理.
研究的目的:
- 审查有关心脏病在认知障碍和痴呆症中的作用的文献.
- 探索"心脏性痴呆"的概念及其潜在机制.
- 强调在脑血管疾病管理中考虑心脏健康的重要性.
主要方法:
- 在50年的时间里进行了全面的文献审查.
- 在主要的科学数据库中进行搜索:eLibrary.ru,CyberLeninka,PubMed,Scopus和谷歌学者.
- 主要搜索词包括"心肌梗塞"",心力衰竭"",心肌疾病"",认知障碍"和"痴呆症".
主要成果:
- 证据支持对"心脏性痴呆"的更广泛的理解, 这是一个近50年前引入的概念.
- 这种机制包括慢性大脑低 perfusion,低度炎症,氧化应激和血脑屏障损伤.
- 连同心肌疾病相关的脑病变中涉及的包括renin- angiotensin- aldosterone和交感神经系统的过度活化.
结论:
- 心脏病在认知障碍和痴呆症的发展中起着关键作用.
- 认可"心脏性痴呆症"需要整合心血管和神经护理方法.
- 进一步研究共享的病因途径可以改善预防和治疗策略.
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