在孕期和孕期糖尿病怀孕中评估胎儿心肌性能指数
Didar Kurt1, Cigdem Kunt Isguder2, Nisa Unlu3
1Department of Obstetrics and Gynecology, Perinatology, Kartal Dr.Lutfi Kirdar City Hospital, Istanbul, Turkey.
Journal of clinical ultrasound : JCU
|August 29, 2025
概括
糖尿病怀孕显示胎儿心脏功能指标升高,特别是心肌性能指数 (MPI) 和同体积缩短时间 (ICT) 升高. 然而,这些指标并不能预测新生儿的不良后果,如新生儿急诊室入院或呼吸应急综合征 (RDS).
科学领域:
- 心脏病学
- 产妇和胎儿医学
- 新生儿学
背景情况:
- 孕期糖尿病,包括孕期糖尿病 (DM) 和孕期糖尿病 (GDM),对胎儿健康构成风险.
- 胎儿心脏功能评估对于监测和管理因糖尿病而复杂的怀孕至关重要.
研究的目的:
- 在孕期DM和GDM的胎儿中评估心肌功能指数 (MPI).
- 评估修改后的MPI与新生儿重症监护室 (NICU) 住院和呼吸应急综合征 (RDS) 等不良周围结果之间的关系.
主要方法:
- 一项涉及157例单独怀孕的病例对照研究: 17例妊娠期DM,52例孕期DM和88例对照.
- 胎儿心声学被用来测量修改的MPI,同体积收缩时间 (ICT),同体积放松时间 (IRT),喷射时间 (ET) 和心肌内.
- 记录和统计分析了新生儿结局,包括新生儿重症监护室和RDS.
主要成果:
- 与对照组相比,患有糖尿病的母亲的胎儿表现出明显更高的修饰MPI和ICT值.
- 妊娠前糖尿病并发症的怀孕中,新生儿重症监护室和RDS的入院率增加.
- 没有发现修改后的MPI与NICU入院或RDS有关.
结论:
- 在糖尿病孕妇中增加的修饰MPI和ICT表明潜在的亚临床胎儿心脏功能障碍.
- 这些心脏功能测量目前无法预测短期新生儿不良结果.
- 需要进一步的前性研究来确定胎儿修饰MPI在糖尿病怀孕的风险分层中的临床效用.
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