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Updated: May 5, 2026

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鼻腔的TFE3-改变的周血管上皮细胞瘤 (PEComa) 具有新的TRAF3::TFE3融合-扩大分子遗传谱的病例报告和头部和部区域PEComa的简要文献综述

Zhengyu Samuel Chua1, Michael Michal2,3, Fredrik Petersson1

  • 1Department of Pathology, National University Hospital, Singapore.

Genes, chromosomes & cancer
|August 29, 2025
PubMed
概括

在一个青少年男性中,一种罕见的鼻周血管上皮细胞瘤 (PEComa) 呈现出一种新的TRAF3:: TFE3基因融合. 这一发现扩大了对头部和部TFE3改变的PEComa的分子理解.

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The Tumor Microenvironment02:17

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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