在患有慢性鼻炎和过敏鼻炎的患者中,对布德塞尼德鼻灌的药物坚持的决定因素
Clifford Jiajun He1, Omer Baker1, Olivia LaMonte2
1School of Medicine, University of California San Diego, La Jolla, California, USA.
International forum of allergy & rhinology
|August 29, 2025
概括
随着时间的推移,对布德索尼德鼻灌的坚持是低的. 诸如鼻不舒服等因素影响了坚持,而手术计划和并发症则对其产生了负面影响.
科学领域:
- 耳鼻喉科
- 鼻炎的研究
- 药理干预措施
背景情况:
- 慢性鼻炎 (CRS) 的治疗通常涉及鼻内治疗.
- 布德塞尼德鼻水是CRS的一种治疗选择.
- 了解患者的坚持是治疗有效性的关键.
研究的目的:
- 评估布德索尼德鼻灌的客观依附率.
- 确定影响患者长期坚持这种治疗的因素.
主要方法:
- 客观地监测布德索尼德的鼻灌使用情况.
- 与患者报告的结果的相关性分析 (鼻不适,SNOT-22).
- 基于手术计划和并发症的坚持评价.
主要成果:
- 对布德索尼德鼻灌的客观依从性一直很低.
- 在研究期间,依从性显著下降.
- 较高的鼻不舒服度与较好的粘附度相关.
- 预计要进行手术的患者和伴随疾病的患者表现较低.
- SNOT-22评分没有预测坚持.
结论:
- 对布德索尼德鼻灌的客观坚持是不理想的,并且随着时间的推移而减弱.
- 与SNOT-22分数不同的是, 鼻不舒服是坚持的积极预测因素.
- 手术前状态和并发症与坚持治疗的减少有关,突出显示了有效治疗的潜在障碍.
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