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Updated: Sep 9, 2025

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通过APEX1-STAT3信号调节力协调的内皮再生

Yueqi Liu1, Chuanrong Zhao1, Zhenhui Liang1

  • 1Department of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, National Health Commission Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Peking University, Beijing, 100191, China.

Cellular and molecular life sciences : CMLS
|August 29, 2025
PubMed
概括

在受伤后,血管壁的刚性会有动态变化,促进内皮再生. 增强的硬度增强了阿普里尼克/ 阿皮里米尼克内核酶1 (APEX1) 和信号转换器和转录激活器3 (STAT3) 的相互作用,推动了细胞修复.

关键词:
内皮功能矩阵的刚性机械力阶段分离重新内皮质化

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