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[DMEK用于穿透角膜整形术后的内皮脱补偿]

Thomas Hammer^1,2, Arne Viestenz³, Christiane Kesper³

¹Universitätsklinikum Halle, Klinik und Poliklinik für Augenheilkunde, Martin-Luther-Universität Halle-Wittenberg, Ernst-Grube-Str. 40, 06120, Halle (Saale), Deutschland. thomas.hammer@uk-halle.de.

Die Ophthalmologie

|August 29, 2025

概括

德塞米特膜内皮切除术 (DMEK) 可以避免内皮切除术的重复. 然而,由于角膜解剖变化, pKPL 后的 DMEK 需要更多的术后再泡.

科学领域:

眼科眼科
角膜外科手术
移植医学

背景情况:

由于更快的恢复和更低的排斥,在内皮角膜疾病中更喜欢Descemet膜内皮角膜整形术 (DMEK),而不是穿透式角膜整形术 (pKPL).
在pKPL之后的内皮解损是DMEK的潜在征兆.

研究的目的:

评估先前pKPL后内皮移植衰竭的患者的DMEK疗效和结果.
在这个特定的患者群体中确定DMEK的术中和术后考虑因素.

主要方法:

在2020-2021年之间进行的10次DMEK手术的回顾性审查.
在手术和术后特征,功能 (视力敏度) 和形态结果的分析.

主要成果:

在10例中,DMEK成功避免了pKPL的重复.
有高的术后气体再注射率 (80%),通常需要多次干预.
视觉敏度显著改善,平均为5. 1线 (logMAR为1. 48至0. 57).

结论:

在pKPL之后,DMEK是一种可行的,最小的侵入性选择,可以避免pKPL的重复.
经过pKPL后的角膜解剖变化需要增加术后监测和干预措施,如重新泡,以确保成功的移植粘附.

关键词:

角膜移植一个DMEK 内皮移植移植失败角质整形

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