为新加坡开发EQ-5D-5L值集
Nan Luo1, Annushiah Vasan Thakumar2, Ling Jie Cheng3,4,5
1Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore. ephln@nus.edu.sg.
PharmacoEconomics
|August 29, 2025
概括
通过复合时间权衡方法开发了新加坡的EQ-5D-5L值. 这个工具反映了新加坡人的健康偏好,
科学领域:
- 健康经济学
- 心理测量
- 生活质量研究
背景情况:
- EQ-5D-5L是一种广泛使用的多属性实用仪器,用于医疗技术评估.
- 开发特定区域的价值集对于准确的健康结果评估至关重要.
研究的目的:
- 开发一个针对新加坡人口的EQ-5D-5L值集.
- 为新加坡提供标准化的健康评估工具.
主要方法:
- 采用了EuroQol研究基金会的估值协议的"简单"版本.
- 综合时间权衡 (cTTO) 任务被分配给500名新加坡居民.
- 交叉验证确定了评估所有3,125个EQ-5D-5L健康状况的最佳模型.
主要成果:
- 一个具有20个参数的主效应模型与两个双向交互项显示出卓越的性能.
- 由此产生的值范围从-0.851 (最差的健康状况) 到1000 (最好的健康状况).
- 疼痛/不适和焦虑/抑郁的维度对不适度做出了最重要的贡献.
结论:
- 为新加坡开发了一套新的EQ-5D-5L值.
- 建议在新加坡使用EQ-5D-5L.
- 鼓励对健康状况评估中的相互作用效应和非线性进行进一步的研究.
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