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Updated: Jun 14, 2026

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综合基因分析确定了肝转移的结直肠癌患者的临床相关预后标志物

Wentao Li1, Ming Liu2, Liula Wu1

  • 1Department of Gastroenteroanal Surgery, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
|August 29, 2025
PubMed
概括

对结直肠肝转移的基因组分析 (CRLM) 确定了关键突变和途径. 整合这些因素可以改善整体存活率的预测,从而更好地分类患者的风险.

关键词:
结直肠肝转移基因组景观一个名字总体生存率预测因素

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...