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相关概念视频

Fatigue01:21

Fatigue

237
Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
237

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Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer
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在多发性硬化症中测量疲劳:快速回顾

Tergel Namsrai1, Anne Parkinson1, Richard Burns1

  • 1National Centre for Epidemiology and Population Health, The Australian National University, Building 63A, Acton, ACT, 2601, Australia.

The patient
|August 29, 2025
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概括

目前的多发性硬化症疲劳度表忽略了患者体验的关键方面. 开发全面的工具需要整合患者的主观数据,以准确测量与MS相关的疲劳触发因素,领域和影响.

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科学领域:

  • 神经学
  • 康复医学
  • 心理学

背景情况:

  • 疲劳是多发性硬化症 (MS) 的普遍和衰弱的症状,通常在临床诊断之前,并表明疾病的进展.
  • 精确测量MS相关的疲劳对于管理和研究至关重要,但目前的工具往往缺乏内容有效性.
  • 现有的疲劳度表可能无法充分反映患有多发性硬化症的个体所经历的多方面的疲劳.

研究的目的:

  • 检查有关MS疲劳的现有文献,以确定其关键方面.
  • 将这些定义的方面与目前在成员国使用的验证疲劳量表的内容进行比较.
  • 发现MS相关疲劳的测量工具的缺陷.

主要方法:

  • 一个综合快速审查 (PROSPERO注册:CRD42024505743) 综合了MS相关疲劳领域的证据,并将其表示在验证的尺度中.
  • 进行了PubMed,Scopus和ProQuest的系统搜索,包括对MS疲劳领域,症状和验证尺度的研究.
  • 数据综合涉及疲劳方面的元聚合,并将其与29个已识别的疲劳测量尺度中的项目进行映射.

主要成果:

  • 包括85项涉及34,984名参与者的研究,确定了791个与疲劳相关的项目,分为触发因素,领域和影响.
  • 确定了8个疲劳触发因素,5个领域 (一般,身体,认知,心理,社会) 和5个影响领域.
  • 虽然有19个经过验证的自我报告尺度,但它们没有完全捕捉到医疗/生活方式触发因素或心理/全球影响,并且没有一个单一的尺度涵盖了所有方面.

结论:

  • 整合患者的主观经验对于开发全面和有意义的工具来衡量多维多样性MS相关的疲劳至关重要.
  • 改善的测量工具对于更好地了解临床实践和研究中的疲劳机制,跟踪和管理至关重要.
  • 更清楚地了解疲劳的触发因素,领域和影响对于推进MS护理至关重要.