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Updated: Sep 9, 2025

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE
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对尼帕病毒5' UTR功能的机械洞察揭示了抗病毒点

Lishi Liu1,2,3, Chaohu Pan4, Zhen Chen1

  • 1Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, 430071, PR China.

The Journal of general virology
|August 29, 2025
PubMed
概括

尼帕病毒 (NiV) 5' UTR 抑制转化,在 C 5' UTR 中有一个特定的热点阻断核糖体启动. 用抗意义寡核酸向这个元素减少了NiV复制,提供了一个潜在的抗病毒策略.

关键词:
5′ UTRs 的时间尼帕病毒 (NiV)另类翻译抗病毒干预有漏洞的扫描

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