近红外光谱 (NIRS) 和儿童皮肤色调:前性队列研究
Joseph R Starnes1, Wendi Welch1, Christopher Henderson1
1Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, 2200 Children's Way, Nashville, TN 37232.
Anesthesiology
|August 29, 2025
概括
近红外光谱 (NIRS) 过度估计了肤色较深的儿童的和度. 这种光学技术的偏见可能会导致医疗保健的不平等. 需要进一步验证NIRS对不同肤色的准确性能.
科学领域:
- 生物医学工程
- 医疗器械
- 临床研究
背景情况:
- 已知脉冲氧计会高估肤色较深的人的和度.
- 近红外光谱 (NIRS) 使用类似的光学原理,但其在不同肤色的准确性不太清楚.
- 调查与皮肤色调相关的NIRS性能对于确保公平的患者监测至关重要.
研究的目的:
- 量化皮肤色调对近红外光谱 (NIRS) 测量准确性的影响.
- 将NIRS衍生的区域氧和与不同肤色的混合静脉和进行比较.
- 识别与皮肤颜色相关的NIRS技术中的潜在偏差.
主要方法:
- 研究了一组110名接受心脏导管治疗的儿科患者.
- 通过光谱测量客观测量皮肤色调,并根据个人类型角度 (ITA) 分类.
- 使用Medtronic INVOS 5100C NIRS装置测量区域氧和,并与混合静脉和进行比较,多变量回归分析了ITA的影响.
主要成果:
- 在NIRS测量中观察到显著的偏差,与较轻的皮肤色调相比,较深的皮肤色调 (ITA 5-6: - 12. 8%) 的平均差异较大 (ITA 3-4: - 2. 5%;ITA 1-2: 0. 3%).
- 个人类型角度 (ITA) 与NIRS偏差显著相关 (系数为0. 173,p<0. 001).
- 观察到的偏差表明,在肤色较暗的个体中,NIRS倾向于报告低于混合静脉和值.
结论:
- 较深的皮肤色调与Medtronic INVOS 5100C NIRS系统较差的性能和低估氧和有关.
- 这种性能差异可能导致患者护理和临床结果的差异.
- 需要加强NIRS设备的验证准则,以确保所有皮肤色的公平性能.
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