Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

557
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
557
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

669
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
669
Glaucoma: Overview01:25

Glaucoma: Overview

745
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
745

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Altered somatosensory profiles in rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, and systemic sclerosis.

EULAR rheumatology open·2026
Same author

Systematic Evaluation of Plasma and Urine Metabolites to Predict the Risk of Adverse Kidney-related Outcomes in Chronic Kidney Disease: The GCKD Study∗.

Kidney medicine·2026
Same author

[<sup>68</sup>Ga]Ga-DOTA-Siglec-9 PET/CT in newly diagnosed giant cell arteritis: an inflammation-specific, treatment-responsive molecular imaging biomarker.

RMD open·2026
Same author

Heterogeneity of Estimated GFR Slopes According to Etiology, Estimated GFR and Urinary Albumin-to-Creatinine Ratio in a Large Cohort of Patients With CKD.

Kidney international reports·2026
Same author

Using the Rate of Global and Pointwise Microperimetry Change to Predict Structural Conversion in Intermediate Age-Related Macular Degeneration.

Ophthalmology science·2025
Same author

Optical coherence tomography angiography detects retinal microvascular changes in giant cell arteritis: the potential protective role of aortitis.

RMD open·2025
Same journal

Use of advanced cardiovascular imaging in rheumatic immune-mediated inflammatory diseases.

Rheumatology (Oxford, England)·2026
Same journal

Comment on: Exploring the effects of GLP-1 receptor agonists in fibromyalgia: a propensity-matched real-world cohort using the TriNetX research platform.

Rheumatology (Oxford, England)·2026
Same journal

Development and validation of a Relapsing Polychondritis disease-specific Quality of Life instrument (ERN ReCONNET RP-QoL).

Rheumatology (Oxford, England)·2026
Same journal

The burden of steroid use in systemic lupus erythematosus.

Rheumatology (Oxford, England)·2026
Same journal

Prognostic value of quantifying vascular inflammation through ultrasound in patients with giant cell arteritis: the MAGiCUS study.

Rheumatology (Oxford, England)·2026
Same journal

A conceptual framework for a RA probability score integrating classification criteria and point-of-care ultrasound in early arthritis.

Rheumatology (Oxford, England)·2026
查看所有相关文章

相关实验视频

Updated: Sep 9, 2025

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
05:20

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

Published on: November 12, 2020

7.6K

透视超声波显示治疗巨细胞动脉炎的视网膜动脉流量和视神经直径持续下降

Simon M Petzinna1, Lara C Burg1, Jan H Terheyden2

  • 1Department of Rheumatology and Clinical Immunology, Clinic of Internal Medicine III, University Hospital of Bonn, Bonn, Germany.

Rheumatology (Oxford, England)
|August 29, 2025
PubMed
概括
此摘要是机器生成的。

在巨细胞动脉炎 (GCA) 患者中,透视超声波 (TOS) 显示了视网膜动脉流量和视神经直径的减少,这表明尽管接受了治疗,眼血管功能仍然受损. 内GCA血管变化可能对治疗反应较差.

关键词:
巨细胞动脉炎炎症发生通过轨道的超声波血管超声波血管炎

更多相关视频

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.5K
The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION
06:49

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION

Published on: November 20, 2016

9.0K

相关实验视频

Last Updated: Sep 9, 2025

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
05:20

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion

Published on: November 12, 2020

7.6K
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.5K
The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION
06:49

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION

Published on: November 20, 2016

9.0K

科学领域:

  • 眼科 眼科
  • 关节病学
  • 血管医学

背景情况:

  • 巨细胞动脉炎 (GCA) 是一种全身性血管炎,可能导致不可逆转的视力丧失.
  • 需要仔细监测和评估治疗疗效.
  • 通过轨道超声波 (TOS) 提供一种非侵入性方法来评估眼血管参数.

研究的目的:

  • 使用TOS对新诊断的GCA患者进行纵向评估.
  • 评估视网膜中枢动脉流速和视神经直径的变化.
  • 将TOS发现与全身血管炎症和治疗反应联系起来.

主要方法:

  • 在12个月内对新诊断的GCA患者进行前性队列研究.
  • 对视网膜中枢动脉的最大抽缩速度 (PSV),终端透析速度 (EDV) 和视神经直径 (OND) 的连续TOS评估.
  • 使用线性混合效应模型计算OMERACT巨细胞动脉炎超声波 (OGUS) 评分和分析.

主要成果:

  • 在12个月的随访期间,PSV和OND显著下降.
  • 症状眼睛的PSV和EDV显著增加.
  • 基线和纵向OGUS得分与PSV,EDV和OND相关,表明正在进行的血管炎症.

结论:

  • 在GCA患者中,TOS显示视网膜动脉流量和OND逐渐减少,表明持续的眼血管功能受损.
  • 内血管的GCA变化可能对治疗的反应不如外血管.
  • 这些发现支持GCA的共享病理生理机制,影响内和外血管.