2型糖尿病的印尼成年人糖尿病视网膜病变和失明的发生率和进展
Muhammad Bayu Sasongko1, Gandhi Anandika Febryanto1, Supanji Haryanto1
1Department of Ophthalmology, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada - Dr. Sardjito General Hospital, Yogyakarta, Indonesia.
PloS one
|August 29, 2025
概括
糖尿病视网膜病变 (DR) 的发生率和进展在2型糖尿病的印尼成年人中进行了研究. 糖尿病持续时间较长显著增加了DR和视力威胁DR (VTDR) 的风险.
科学领域:
- 眼科 眼科
- 内分泌学
- 公共卫生
背景情况:
- 糖尿病视网膜病变 (DR) 是可预防的失明的主要原因.
- 印度尼西亚有相当一部分成年人患有2型糖尿病.
- 了解DR的发病率和进展对于公共卫生干预至关重要.
研究的目的:
- 确定糖尿病视网膜病变 (DR) 和失明的发生率和进展率.
- 确定与2型糖尿病的印尼成年人中DR和失明相关的危险因素.
主要方法:
- 在899名30岁以上的2型糖尿病患者中进行前性队列研究.
- 标准化的临床和眼睛检查,包括双场视网膜摄影.
- 蒙面评分器对DR进行分类;分类包括非增殖性DR (NPDR),增殖性DR (PDR) 和视力威胁性DR (VTDR).
主要成果:
- 每 1000 人/ 年的DR和VTDR发病率分别为34. 6和24. 5.
- 糖尿病持续时间较长增加了在5年内发展DR (HR1.37),VTDR (HR2.00) 和进展DR (HR1.50) 的风险.
- 肥胖,疹和神经病变与DR风险或进展的增加有关; 农村生活增加了失明风险.
结论:
- 印度尼西亚2型糖尿病患者中DR,VTDR和失明的发病率和进展率.
- 糖尿病持续时间较长是5年内DR和VTDR发展的重要风险因素.
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