重症跨性别患者的内分泌问题:叙述性回顾
Charalampos Milionis1, Emmanouil Zoumakis2, Athanasios Tselebis3
1Department of Endocrinology, Diabetes and Metabolism, Elena Venizelou General Hospital, Athens 11521, Greece.
World journal of critical care medicine
|August 29, 2025
概括
性别确认激素治疗 (GAHT) 在重症监护中提出了独特的挑战. 由于复杂的内分泌相互作用,对变性患者进行仔细监测和个性化治疗至关重要.
科学领域:
- 危急护理医学
- 内分泌学
- 跨性别者健康
背景情况:
- 性别确认激素治疗 (GAHT) 对变性人来说至关重要.
- 危急的疾病使GAHT患者的治疗复杂化.
- GAHT会影响内分泌和代谢的参数.
研究的目的:
- 探索治疗严重疾病的跨性别患者的复杂性.
- 突出在危急疾病中由GAHT相互作用引起的潜在并发症.
- 强调需要个性化照顾和监控.
主要方法:
- 对高血压和严重疾病的现有文献的审查.
- 与GAHT相关的内分泌和代谢变化的分析.
- 鉴定血栓栓塞和药物相互作用等风险.
主要成果:
- 雌激素治疗增加了跨性别女性的静脉血栓塞栓风险.
- 治疗可能导致红细胞形成,增加跨性别男性的血栓塞栓风险.
- GAHT可以改变脑下垂体上腺轴的功能和荷尔蒙水平.
结论:
- 需要仔细考虑激素效应和药物相互作用.
- 个性化治疗计划和对内分泌和代谢参数的警监测至关重要.
- 缺乏以证据为基础的指导方针需要谨慎的,针对患者的方法.
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