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与COVID-19相关的败血症冲击中的种族和种族差异
Song-Peng Ang1, Jia-Ee Chia2, Maria Jose Lorenzo-Capps1
1Department of Internal Medicine, Rutgers Health Community Medical Center, Toms River, NJ 08755, United States.
World journal of critical care medicine
|August 29, 2025
概括
与非西班牙裔白人患者相比,患有COVID-19相关的败血症的西班牙裔和非西班牙裔黑人患者面临更高的死亡风险和急性损伤等并发症,需要透析和机械通风.
科学领域:
- 危急护理医学
- 感染性疾病
- 健康差异研究
背景情况:
- 败血症是一种严重的败血症,
- 由于COVID-19大流行,感染SARS-CoV-2导致的败血症和败血性休克的负担增加了.
- 现有的数据显示严重疾病的结果存在种族和种族差异,但它们对COVID-19相关的败血症冲击的具体影响尚不清楚.
研究的目的:
- 调查与COVID-19相关的感染性休克患者的结果的种族和种族差异.
- 分析流行病学数据以确定基于种族和种族的重症监护结果的差异.
主要方法:
- 使用国家住院患者样本 (2020-2021) 进行了回顾性队列研究.
- 这项研究包括了同时患有COVID-19和败血症的成年患者 (≥18岁).
- 通过调整的多变量逻辑回归来评估住院死亡率,急性损伤 (AKI),需要透析的AKI和机械呼吸等结果.
主要成果:
- 与非西班牙裔白人患者相比,西班牙裔患者的住院死亡率更高,机械呼吸的需求增加,需要透析的AKI风险更高.
- 非西班牙裔黑人患者的死亡率与非西班牙裔白人患者相似,但机械呼吸和需要透析的AKI风险更高.
- 西班牙裔患者住院时间最长,相关费用最高.
结论:
- 患有COVID-19相关的败血症的西班牙裔患者死亡率较高.
- 与非西班牙裔白人相比,西班牙裔和非西班牙裔黑人患者群体的脏和呼吸道并发症增加.
- 需要进一步的研究来确定这些差异的原因,并制定针对早期发现和降低风险因素的有针对性的战略.
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