感染性休克患者的种族差异:国家队列研究
Song-Peng Ang1, Jia-Ee Chia2, Jose Iglesias3,4,5
1Department of Internal Medicine, Rutgers The State University of New Jersey, Toms River, NJ 08755, United States.
World journal of critical care medicine
|August 29, 2025
概括
感染性休克的种族差异仍然存在,非西班牙裔黑人和西班牙裔患者的住院死亡率更高. 这些群体也经历了更长的住院时间和更高的费用,强调了有针对性的干预措施的必要性.
科学领域:
- 危急护理医学
- 公共卫生
- 健康差异研究
背景情况:
- 败血症和败血性休克是严重的公共卫生问题,死亡率很高,特别是在重症监护机构.
- 现有研究表明血发病率存在种族差异,但对患者结果的影响尚未得到一致定义.
研究的目的:
- 调查因败血症而入院患者的临床结果的种族差异.
- 关注的领域包括住院死亡率,住院时间 (LOS) 和相关住院费用.
主要方法:
- 一项回顾性队列研究利用了国家住院样本数据库 (2016-2021) 的数据.
- 使用ICD-10代码R65.21识别了败血性休克病例.
- 主要终点是住院死亡率;次要终点包括住院趋势,LOS和成本.
主要成果:
- 这项研究分析了3,581,504例感染性休克病例. 非西班牙裔白人为67%,非西班牙裔黑人为15%,西班牙裔为11%,其他群体为7%.
- 整体住院死亡率为33.6%,在"其他"种族群体中最高 (36.7%). 2020-2021年死亡率显著增加,特别是在西班牙裔患者中.
- 与非西班牙裔白人 (NHW) 患者相比,调整后的分析显示NHB和西班牙裔患者的死亡率更高. 而"其他"群体的费用最高.
结论:
- 在NHB,西班牙裔和其他种族群体中观察到更高的住院死亡率.
- 这些不良结果可能与这些人群的住院并发症风险增加有关.
- 进一步的研究是必要的,以确定导致这些差异的具体因素,并为干预提供信息.
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