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在小鼠模型中,聚达丁通过向Aqp5来改善过

Jian-Feng Chen1,2, Zhi Feng1,2, Feng-Qiang Yu1,2

  • 1Department of Thoracic Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.

Frontiers in pharmacology
|August 29, 2025
PubMed
概括

通过向Aquaporin 5 (AQP5) 和关键的神经因子,聚达丁有效地减少过度出汗. 这种天然化合物被认为是治疗原发性焦点性水 (PFH) 的新药.

关键词:
水族素5聚达丁主要焦点过汗腺治疗方法

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Aquaporins01:25

Aquaporins

Aquaporins or AQPs are a family of integral membrane proteins whose primary function is to transport water, while some called aquaglyceroporins also transport glycerol. In addition, aquaporins have also been suspected to be involved in transporting volatile substances, such as carbon dioxide and ammonia, across membranes. Such AQPs that act as gas channels are often highly expressed in cells involved in the gaseous exchange, such as red blood cells, epithelial cells, and pulmonary capillaries.
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