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相关概念视频

The Spinal Cord01:54

The Spinal Cord

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The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
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Spinal Cord01:26

Spinal Cord

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The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
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Spinal Nerves: Plexus I01:22

Spinal Nerves: Plexus I

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Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
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Spinal Nerves: Plexus II01:21

Spinal Nerves: Plexus II

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The plexuses of the lower body include the lumbar, sacral, and coccygeal plexuses, which innervate the abdomen, pelvis, legs, and coccygeal region. These plexuses control the transmission of sensory information and coordinate motor functions of the lower body.
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
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Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
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Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

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The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
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相关实验视频

Updated: Sep 9, 2025

Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord
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基于PAM50脊髓模板的注册

Sandrine Bédard1, Jan Valošek1,2,3,4, Valeria Oliva5,6

  • 1NeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada.

Imaging neuroscience (Cambridge, Mass.)
|August 29, 2025
PubMed
概括

使用神经根的新脊髓成像方法改善了功能性MRI (fMRI) 组分析的解剖对齐. 这种基于rootlet的注册增强了准确性和可重复性,导致更可靠的神经成像结果.

关键词:
神经根子进行注册空间规范化脊髓一个模板

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Studying the Coding Profiles of Somatic Stimulation on Cardiac-locked Neuronal Responses in the Rat Spinal Dorsal Horn
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Author Spotlight: Innovative Methodology for Implanting and Securing Neural Probes in the Rodent Spinal Cord
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科学领域:

  • 神经成像
  • 脊髓的解剖学
  • 医学图像分析

背景情况:

  • 脊髓功能性MRI (fMRI) 需要精确的解剖学定位进行组分析.
  • 使用椎间盘进行注册的传统方法存在解剖学变异性.
  • 在脊髓研究中,改善对齐对于可靠的语音组分析至关重要.

研究的目的:

  • 开发和验证使用背部根的脊髓fMRI的新注册方法.
  • 为了提高对齐准确度和可重复性,在不同个体和不同的部位置.
  • 将基于rootlet的注册与基于磁盘的传统方法在组级fMRI分析中的性能进行比较.

主要方法:

  • 开发了一种非线性注册方法,将细分的背部根与PAM50脊髓模板对齐.
  • 在大型多个受试者,多个地点的数据集 (n=267) 和不同部位置的数据集 (n=10) 上验证了该方法.
  • 基于任务的fMRI (n=23) 的组级激活图与基于磁盘的注册进行了比较.

主要成果:

  • 与基于磁盘的方法相比,基于rootlet的注册在226个个体的一般分析和176个个体的形态分析中显示出优异的对齐.
  • 不同的部位置显示出更大的稳定性.
  • 基于任务的fMRI分析显示Z得分增加,激活集群大小显著增加 (3292至7978个voxel),基于rootlet的注册.

结论:

  • 基于rootlet的注册显著改善了脊髓成像中的内部和内部解剖对齐.
  • 这种方法增强了群体级fMRI分析的空间规范化,提高了精度和可靠性.
  • 这些发现支持基于根子的注册在推进脊髓神经成像方面的潜力.