糖尿病患者的眼内压力变化 (眼高血压)
Sony Sinha1, Prateek Nishant2, Arvind Kumar Morya3
1Department of Ophthalmology Vitreo-Retina, Neuro-Ophthalmology and Oculoplasty, All India Institute of Medical Sciences, Patna 801507, Bihar, India.
World journal of clinical cases
|August 29, 2025
概括
眼睛高血压 (OHT) 会增加青光眼的风险. 本综述探讨了OHT和糖尿病之间的复杂关系,并指出了共同的血管因素和对眼睛健康的潜在影响.
科学领域:
- 眼科 眼科
- 内分泌学
- 血管生物学
背景情况:
- 眼睛高血压 (OHT) 是高眼内压 (IOP) 没有视神经损伤,这是青光眼的关键危险因素.
- OHT和糖尿病之间的联系尚未完全理解,但这两种情况都会影响眼睛的循环.
- 共同的风险因素如高血压和血管损害使OHT-DM关联复杂化.
研究的目的:
- 综合审查眼睛高血压和糖尿病之间的联系.
- 阐明多因素关系,包括血管,自主和遗传影响.
主要方法:
- 对研究OHT,IOP,DM和相关眼部并发症的文献综述.
- 分析糖尿病患者内压升高的机制,如透梯度和状网格变化.
- 检查糖尿病视网膜病变及其治疗对内膜压力的影响.
主要成果:
- 在DM患者中,内压升高可能源于水性透梯度和状网状结构的改变.
- OHT可与糖尿病视网膜病变一起发生或不发生;一些DR治疗会影响内血压.
- IOP是DR的独立风险因素,高血压等并发症与OHT和DM有关.
结论:
- OHT和DM之间的相互作用是复杂的,涉及共同的血管病理和与治疗有关的影响.
- 了解这些关联对于控制糖尿病患者的青光眼风险至关重要.
- 需要进一步研究以澄清具体机制并指导临床实践.
相关概念视频
Glaucoma: Overview
745
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
745
Open Angle Glaucoma: Treatment
557
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
557
Diabetes Mellitus: Type 2 and Gestational
2.9K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.9K
Angle Closure Glaucoma: Treatment
669
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
669
Diabetes Mellitus: Overview and Type I Subtype
3.2K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
3.2K
Pathophysiology of Diabetes
1.2K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.2K


