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在功能上胃肠道疾病中探索小肠道细菌过度生长:综合病例对照研究
Bhaswati C Acharyya1,2, Meghdeep Mukhopadhyay1
1Department of Pediatric Gastroenterology and Hepatology, Institute of Child Health, Kolkata 700017, West Bengal, India.
World journal of clinical pediatrics
|August 29, 2025
概括
小肠细菌过度生长 (SIBO) 是常见的儿童上部肠道症状无法解释. 建议对这些儿科患者进行SIBO检查,即使内镜检查结果正常.
科学领域:
- 儿童胃肠病学
- 微生物组研究
- 诊断的准确性
背景情况:
- 在功能性胃肠疾病中经常怀疑细肠细菌过度生长 (SIBO).
- 有上部肠道症状的儿童通常不会进行SIBO测试.
研究的目的:
- 确定SIBO在具有功能上肠道症状的儿童中的流行率.
- 为了比较有内镜病变和没有内镜病变的儿童的SIBO状态.
主要方法:
- 在使用质子抑制剂 (PPI) 之前,129名患有上部肠道症状的儿童接受了内镜检查.
- 病例的内镜检查正常;对照组的内镜病变.
- 在两组中都诊断出SIBO.
主要成果:
- 在正常内镜检查的儿童中,SIBO被诊断为59%,而在病变检查的儿童中,SIBO被诊断为21%.
- 在病例中SIBO的概率为5. 38,表明了显著的关联.
- 恶心,恶臭和胃上充满预测了儿童的SIBO.
结论:
- 对于内镜无法解释的上部肠道症状的儿童,SIBO检查很有价值.
- 早期的SIBO诊断和治疗可以改善儿童的胃肠道健康结果.
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