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Updated: Jun 28, 2026

Generation of Human Blood Vessel Organoids from Pluripotent Stem Cells
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使用可扩展的微流体平台从人类多能干细胞中持续生产高功能血管化肝胆器官

Saeed Abbasalizadeh1,2,3,4, Sahab Babaee4,5,6, Reza Kowsari-Esfahan2

  • 1Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

Advanced functional materials
|August 29, 2025
PubMed
概括

研究人员开发了可扩展的平台,用于从人类多能干细胞 (hPSC) 产生血管化的肝脏器官. 这些器官模仿胎儿和成年人的肝功能,进步了慢性肝病治疗和药物开发的器官医学.

关键词:
有机物水凝微流体复原医学

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Liver Regeneration01:24

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The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...