桥式亚烯表现出完全可逆的光控制结合到G-四重体DNA/双重体结合

Javier Ramos-Soriano1, Y Jennifer Jiang1, Bowen Deng1,2

  • 1School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, United Kingdom.

JACS Au
|August 29, 2025
PubMed
概括

研究人员开发了一种光控制的分子,可选择性地与特定的DNA结构结合,如HIV-1 LTR-III G-四重复 (G4). 这一突破使得使用可见光对DNA结合进行可逆控制,

相关概念视频

Aryldiazonium Salts to Azo Dyes: Diazo Coupling01:11

Aryldiazonium Salts to Azo Dyes: Diazo Coupling

The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
3.1K