在阻塞性睡眠呼吸暂停患者中,NoSAS评分与心血管疾病之间的关联
Riken Chen1, Jie Quan2, Qiujing Tang3
1Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
通过NoSAS得分识别的阻塞性睡眠呼吸暂停 (OSA) 的高风险与心血管疾病的风险显著增加有关,特别是在老年人中. 早期查对于干预至关重要.
科学领域:
- 睡眠医学
- 心脏病学
- 公共卫生
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种普遍但经常未被诊断的睡眠障碍.
- OSA与不良健康结果,特别是心血管并发症密切相关.
- 早期发现OSA对于及时干预和改善患者的结果至关重要.
研究的目的:
- 评估NoSAS评分在识别患有OSA高风险的个人的有效性.
- 研究高风险OSA分类 (使用NoSAS评分) 与心血管疾病 (CVD) 发病率之间的关联.
- 确定NoSAS得分是否可以作为心血管疾病的独立预测指标.
主要方法:
- 从睡眠医学中心分析了2,164名参与者的数据.
- 参与者被分为高风险 (NoSAS评分≥8) 或低风险 (NoSAS评分<3).
- 用物流回归分析来评估高风险的OSA和心血管疾病发病率之间的关系.
主要成果:
- 高风险OSA组 (1,248名参与者) 的心血管疾病发病率为7. 29%.
- 高风险的OSA分类独立地与心血管疾病风险增加2.2倍相关 (OR:2.22,95% CI:1.17- 4.18,p=0.006).
- 在60岁及以上的参与者中观察到NoSAS风险分类与心血管疾病之间的显著关联.
结论:
- 通过NoSAS得分,有效地识别出具有阻塞性睡眠呼吸暂停高风险的个体.
- 根据NoSAS得分,高风险的OSA是心血管疾病的独立预测指标.
- 这些发现突显了NoSAS得分在OSA患者心血管风险管理中的重要性.
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