肝移植后患者的体外疗法:最难走的路
Anant Vikram Pachisia1, Deepak Govil2, K N Jagadeesh1
1Institute of Critical Care and Anesthesiology, Medanta-The Medicity, Gurugram 122001, Haryana, India.
World journal of transplantation
|August 29, 2025
概括
外体疗法通过管理并发症来支持肝移植患者. 本综述探讨了传染性和非传染性问题的不断发展的治疗方法,旨在改善肝移植后的结果.
科学领域:
- 肝病学
- 移植医学
- 临床护理 科
背景情况:
- 外体疗法对于急性和慢性肝衰竭患者至关重要,作为肝移植的桥梁.
- 肝移植的成功率越来越高,导致术后并发症的范围越来越广.
- 关于肝脏移植后期体外治疗的文献有限.
研究的目的:
- 审查正在发展的用于治疗肝移植患者并发症的体外疗法.
- 讨论感染性和非感染性并发症的治疗方法.
- 要突出证据有限但有可能改善患者的结果的领域.
主要方法:
- 对肝移植的体外疗法的当前文献进行系统审查.
- 将治疗方法分为感染性并发症和非感染性并发症.
- 具体技术的讨论,包括吸附柱,等离子体交换等.
主要成果:
- 外体疗法分为针对传染性并发症 (例如内毒素/细胞因子吸附) 和非传染性并发症 (例如小于大小的综合征,移植功能障碍) 的类型.
- 特定的非感染性并发症治疗包括血交换,双重血分子吸附,分子吸附剂循环系统和体外膜氧化.
- 在移植后的环境中,一些正在发展的体外疗法的证据有限但有希望.
结论:
- 外体疗法在治疗肝移植后的一系列并发症方面具有潜在的益处.
- 需要进一步的研究和临床试验来确定正在发展的体外疗法的有效性.
- 这些先进的疗法可以显著改善肝移植患者面临复杂的术后挑战的结果.
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