通过扩展 (12区域) 和传统 (6区域) 肺超声波评分进行新生儿评估 (NEXT-LUS):前性观察性研究
Chinmay Chetan1, Shoham Majumder2, Aninda Debnath3
1Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, India.
Frontiers in pediatrics
|August 29, 2025
概括
新生儿呼吸困难的肺部超声波得分准确地预测了侵入性通风的需要. 6区域和12区域肺超声波 (LUS) 方法在72小时内显示出可比的预测值.
科学领域:
- 新生儿医学
- 儿童肺病学
- 医学成像
背景情况:
- 肺部超声波 (LUS) 是一种安全的无辐射工具,用于治疗新生儿呼吸困难.
- 对于新生儿的最佳LUS评分方法存在有限的数据.
研究的目的:
- 评估6区域和12区域LUS评分对新生儿的侵入性通风的预测值.
- 比较不同的LUS评分方法的准确性和程序安全性.
主要方法:
- 在第三级新生儿重症监护室 (NICU) 进行前性观察研究.
- 在入院2小时内出现呼吸困难的新生儿.
- 使用Brat的评分标准进行6区和12区LUS扫描.
主要成果:
- 6区域LUS得分 (切断值≥5) 和12区域LUS得分 (切断值≥13) 在预测侵入性通风时具有相似的准确性 (AUCs~0.76-0.77).
- 在早产新生儿 (<34周) 和晚产新生儿 (24小时后) 中,这两种评分都表现更好.
- 6区分的程序安全性更好,12区分的程序安全性需要在9%的案例中重新尝试.
结论:
- 6区域和12区域的LUS分数在预测 72小时内患有呼吸困难的新生儿需要侵入性通风时是有效和可比的.
- 建议采用6区LUS方法,因为该方法的简单性和安全性.
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