Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

136
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
136
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

98
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
98

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Distal Recirculation of Enteral contents Augmented Mechanically (DREAM) Promotes Intestinal Adaptation and Restores Enterohepatic Signaling in Short Bowel Syndrome.

Gastroenterology·2026
Same author

Exploring role of therapeutic plasma exchange for hepatitis A-related acute liver failure: An Indian multi-center cohort study.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology·2026
Same author

Chronic in utero oxycodone exposure alters placental small EV proteome and fetal cardiomyopathy-linked pathways.

Extracellular vesicles and circulating nucleic acids·2026
Same author

Peptide-Based Probe Targeting Angiotensin Type‑1 Receptor Identifies Pancreatic Ductal Adenocarcinoma Using Multispectral Optoacoustic Tomography.

Chemical & biomedical imaging·2026
Same author

Viscous energy dissipation on hemolysis across various flow regimes using a high-shear device.

Medical engineering & physics·2026
Same author

Indian National Association for Study of the Liver Guidance Document on Difficult to Treat Autoimmune Hepatitis.

Journal of clinical and experimental hepatology·2026

相关实验视频

Updated: Sep 9, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

29.3K

评估肠道微生物群的生物信息学方法

James Douglas Fox1, Austin Sims1, Morgan Ross1

  • 1Department of Pediatrics, Saint Louis University, St. Louis, MO 63103, USA.

Microbiology research
|August 29, 2025
PubMed
概括

生物信息学方法使用16S rRNA和全基因组测序等测序技术分析肠道微生物群. 本文将这些方法进行比较,以了解肠道微生物组在健康和疾病中的作用.

关键词:
16S rRNA 测序生物信息学胃肠道疾病肠道微生物群肠道微生物学微生物组猎枪测序全基因组测序

更多相关视频

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
06:58

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Published on: August 23, 2019

7.2K
A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
07:54

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice

Published on: July 25, 2017

14.4K

相关实验视频

Last Updated: Sep 9, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

29.3K
Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
06:58

Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems

Published on: August 23, 2019

7.2K
A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
07:54

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice

Published on: July 25, 2017

14.4K

科学领域:

  • 微生物学
  • 生物信息学
  • 基因组学

背景情况:

  • 肠道微生物群分析对于了解人类健康和疾病至关重要.
  • 生物信息工具对于解释复杂的微生物社区数据至关重要.
  • 高通量测序为微生物组研究产生了庞大的数据集.

研究的目的:

  • 为了比较16S rRNA基因测序和全基因组测序方法.
  • 阐明这些测序方法的利用和潜力的差异.
  • 增强对肠道微生物组在人类生理和病理方面的理解.

主要方法:

  • 对肠道微生物群评估的生物信息学方法的审查.
  • 高通量测序技术 (16S rRNA,元基因组学,全基因组) 的分析.
  • 讨论生物信息学工具,算法和数据解释的统计模型.

主要成果:

  • 16S rRNA测序提供了微生物多样性和分类信息.
  • 全基因组测序提供了更深入的功能潜力,但成本更高.
  • 生物信息学可以识别微生物种类及其作用.

结论:

  • 生物信息学方法对于破译肠道微生物群的复杂性至关重要.
  • 了解测序方法的差异有助于微生物组研究和治疗开发.
  • 优化微生物组分析是未来健康干预的关键.