为艾滋病毒感染者和吸毒者提供数字健康支持的卫生系统层面实施:集群随机阶段临床试验协议
Ryan P Westergaard1,2, Hailey K Ballard1, Rachel E Gicquelais1,2
1Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, United States.
JMIR research protocols
|August 29, 2025
概括
移动卫生系统ART-C旨在改善艾滋病毒和物质使用障碍患者的病毒抑制. 这项研究评估了它在提高护理参与度和健康结果方面的有效性.
科学领域:
- 数字健康
- 艾滋病毒药物
- 公共卫生
背景情况:
- 艾滋病毒感染者 (PLWH) 面临物质使用障碍 (SUD) 和社会脆弱性,难以抑制病毒.
- 移动卫生系统提供了增强社会和行为支持的潜力,以改善艾滋病毒的结果.
研究的目的:
- 实施和评估抗逆转录病毒治疗护理协调 (ART-C) 数字健康系统.
- 改善艾滋病毒抑制,减少多站点艾滋病毒护理计划中错过的诊所访问.
主要方法:
- 在多个州的8个Vivent健康诊所实施ART-C.
- 使用定制的智能手机应用程序 (Connections) 提供同行支持,并为SUD患者提供增强功能.
- 阶段性临床试验设计以评估有效性和实施混合方法.
主要成果:
- 在实施前的数据显示,有显著的失诊率 (45- 70%) 和病毒不抑制率 (14-37%).
- 在6710名患者中,25. 68%的患者有SUD,42. 1%的患者没有去看病,20. 18%的患者有病毒不抑制.
- 招募了86名参与者;数据收集持续到2027年.
结论:
- 该研究将评估SUD的PLWH移动健康干预的有效性.
- 将评估ART-C的实施策略,以支持护理参与和病毒抑制.
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