,

Hongjie Zhang1, Zehua Jiang2, Ziyang Liu3

  • 1Department of Orthopedics, The People's Hospital of Dehong/Kunming Medical University Affiliated Dehong Hospital, Mangshi 678400, China; Department of Spine Surgery, Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin 300121, China.

概括

增加膝关节角会增加机械应力,通过Piezo1引发淋巴细胞亡. 这种途径加速了骨关节炎的进展,确定了Piezo1作为软骨退化的治疗点.