基于pH的Zain花生蛋白分离复合纳米颗粒用于稳定皮克林乳液并增强复星的输送
Sufang Chen1, Weiwei Cheng2, Wenrui Liu1
1College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471000, China.
International journal of biological macromolecules
|August 29, 2025
概括
复合纳米颗粒增强了功能性食品的皮克林乳液稳定性和复星封装. 这些纳米颗粒提供了卓越的体稳定性和改善的生物活性传递,显示出对食品应用的希望.
科学领域:
- 食品科学与技术
- 材料科学
- 生物技术
背景情况:
- 对于功能性食品来说,开发稳定的脂性生物活性物质传递系统至关重要.
- 基于蛋白质的纳米粒子提供生物相容和可生物降解的封装解决方案.
- 和花生蛋白分离物 (PPI) 是丰富的植物蛋白质,具有纳米粒子制造的潜力.
研究的目的:
- 使用pH驱动自组装制造Zeen-PPI复合纳米粒子.
- 评估它们在稳定皮克林乳液中的性能.
- 探索它们在封装和输送复星的有效性.
主要方法:
- 通过pH驱动自组装制造Zeen-PPI复合纳米粒子.
- 粒子特性 (大小,PDI,泽塔电位,表面可湿性) 的表征.
- 对皮克林乳液稳定,囊化和体外消化进行评估.
主要成果:
- 1:2的Zeen:PPI比率产生了最佳的纳米粒子 (389nm,PDI 0.32,-42mV) 具有增强的体稳定性.
- 复合纳米粒子形成了稳定的油在水皮克林乳液,具有出色的热,pH和盐稳定性.
- 在模拟消化过程中,复星封装效率达到86. 5%,抗氧化能力提高,生物可获得性提高 (> 40%).
结论:
- Zein-PPI复合纳米颗粒为皮克林乳液稳定提供了稳定有效的平台.
- 这些纳米颗粒显著增强了复醇的封装和输送,提高了其生物可访问性和稳定性.
- 开发的系统显示了创造功能性食品的巨大潜力,并改善了脂溶性生物活性物质的输送.
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