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Updated: Sep 9, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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在复发性/耐火性多发性骨髓瘤中使用利多米德,环胺和德克萨米:单中心实验

Ioannis Ntanasis-Stathopoulos1, Panagiotis Malandrakis1, Charalampos Filippatos1

  • 1Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Clinical lymphoma, myeloma & leukemia
|August 29, 2025
PubMed
概括

在复发性/ 耐药性多发性骨髓瘤 (RRMM) 患者中,PCd疗法 (波马利多米德,环胺和德克萨米) 显示出有希望的疗效. 高风险细胞遗传学对结果产生了负面影响,而中性质衰竭是最常见的严重毒性.

关键词:
多发性骨髓瘤生存情况三人组

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