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Updated: Sep 9, 2025

An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions
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通过细胞状态来揭示因果调节机制

Alexander P Wu1, Rohit Singh2,3,4, Christopher A Walsh5,6,7

  • 1Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA.

Nature communications
|August 29, 2025
PubMed
概括

我们开发了一种新型图形神经网络, 以揭示非编码基因变异与单细胞基因调节之间的因果关系. 这种方法以"细胞状态"为灵感, 提高了对精神分裂症等复杂疾病的理解.

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