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Updated: Sep 9, 2025

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs
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在15q11.2删除相关神经发育障碍的人类神经元模型中改变发育和网络连接

Christa W Habela1, Shiyu Liu2, Arens Taga2

  • 1Department of Neurology, Johns Hopkins University, Baltimore, MD, USA. chabela1@jh.edu.

Translational psychiatry
|August 29, 2025
PubMed
概括

删除15q11.2染色体会损害皮质神经元的发育,导致连接减少和网络功能发生改变. 这种遗传原因影响神经元结构和活动,可能解释相关的神经发育障碍.

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