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Updated: Sep 9, 2025

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GD2TIF细胞作为单剂量和长期生物药物的平台

Guangyue Zhang1,2,3,4,5,6, Na Yin1,2,3,4,5,6, Min Peng7,8,9,10,11,12

  • 1State Key Laboratory of Molecular Oncology, Tsinghua University, Beijing, China.

Nature communications
|August 29, 2025
PubMed
概括

工程T细胞为长期的生物输送提供了一个新的解决方案. 这些"不朽的"GD2 CAR T细胞 (GD2TIF) 在一次输液中提供持续的治疗效果,克服了短的药物半衰期.

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Drug Delivery: Overview01:16

Drug Delivery: Overview

The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
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