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作者反思:新辅助系统治疗后的PET/CT反应评估是否足以治疗III期黑色素瘤?

Ronen Stoff1, Matthew S Block2, Tina J Hieken3

  • 1Department of Oncology, Mayo Clinic, Rochester, MN, USA. Stoff.ronen@mayo.edu.

Annals of surgical oncology
|August 29, 2025
PubMed
概括

No abstract available in PubMed .

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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