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Updated: Sep 9, 2025

Orthotopic Injection of Breast Cancer Cells into the Mammary Fat Pad of Mice to Study Tumor Growth.
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局部重编程与瘤相关的巨细胞用细胞因子载入的可注射冷凝治疗乳腺癌

Sydney R Henriques1, Evan B Glass1, Kristen L Hoek2

  • 1Department of Biomedical Engineering, Vanderbilt University, Nashville, USA.

Annals of biomedical engineering
|August 29, 2025
PubMed
概括

可注射的酸盐冷凝将免疫抑制瘤相关的巨细胞 (TAM) 重编成一种类似M1的抗瘤状态. 这种局部治疗通过创建炎症性瘤微环境 (TME) 来减少乳腺瘤生长和T细胞疲劳.

关键词:
乳腺癌冰冷凝细胞因子免疫疗法巨细胞瘤微环境

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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