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研究领域工程学化学工程过程控制和模拟
编辑表达关注:开发一种体外裂解测定系统来检测疫苗病毒I7L囊蛋白酶活性

编辑表达关注:开发一种体外裂解测定系统来检测疫苗病毒I7L囊蛋白酶活性

Chelsea M Byrd ¹, Dennis E Hruby ^2,3

Chelsea M Byrd ¹, Dennis E Hruby ^2,3

¹Molecular and Cellular Biology Program, Oregon State University, 220 Nash Hall, Corvallis, Oregon, 97331, USA.
²Molecular and Cellular Biology Program, Oregon State University, 220 Nash Hall, Corvallis, Oregon, 97331, USA. dhruby@sgph.com.
³Siga Technologies, 4575 SW Research Way, Suite 230, Corvallis, Oregon, 97333, USA. dhruby@sgph.com.

⁰Molecular and Cellular Biology Program, Oregon State University, 220 Nash Hall, Corvallis, Oregon, 97331, USA.

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2025年八月29日

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概括

No abstract available on PubMed

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相关概念视频

In-vitro Mutagenesis

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

The Process

Genes can be randomly knocked out, or specific genes can be targeted. To knock out a particular gene, an engineered piece of DNA called a targeting vector is used...

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