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Updated: Sep 9, 2025

Exploring the Arginine Methylome by Nuclear Magnetic Resonance Spectroscopy
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低氧诱导的PRMT1乳化促使瘤转移中的维门丁氨酸不对称二甲基化

Jia Zhou1, Shuying Qiu1, Xia Yang2

  • 1Department of Medical Oncology, Cancer Center of Zhejiang University, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310016, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|August 30, 2025
PubMed
概括

低氧会触发蛋白质阿尔金因甲基转移酶1 (PRMT1) 乳化,增加其活性以修改维门丁并驱动癌症转移. 针对这种低氧-PRMT1-维门丁轴提供了一种新的抗转移策略.

关键词:
一个 PRMT氨酸甲基化癌症转移没有氧气乳酸化维门

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