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左心室中风工作指数作为跨导管大动脉植入后大动脉狭窄的预测指标

Hiroyuki Iwano^1,2, Kimi Sato³, Noor Albakaa³

¹Division of Cardiology, Teine Keijinkai Hospital, Sapporo, Japan.

Echocardiography (Mount Kisco, N.Y.)

|August 30, 2025

概括

在跨导管主动脉植入之前,主动脉狭窄患者的中风工作指数 (SWI) 降低预示着不良结果. 结合SWI和全球纵向应变 (GLS) 评估可以改善这些患者的风险分层.

科学领域:

心脏病学
心声检查
心脏外科

背景情况:

评估左心室 (LV) 收缩性以预测大动脉狭窄 (AS) 的结果是复杂的,因为全球纵向应变 (GLS) 不考虑后负荷.
脑中风工作指数 (SWI) 提供了LV外部工作的另一个心声测量方法.

研究的目的:

在接受过导管主动脉植入 (TAVI) 的AS患者中评估LV SWI的预后值.
评估SWI是否可以独立于其他临床因素来预测结果.

主要方法:

一个多中心的回顾性研究包括1583名接受TAVI的患者.
使用心声学参数计算LV SWI;可获得902名患者的GLS数据.
主要终点是心脏死亡或心力衰竭恶化.

主要成果:

较低的LVSWI与明显较低的无事件存活率有关.
在考克斯回归分析中,LV SWI独立预测了主要终点.
在降低GLS的患者中,LV SWI有效区分无事件存活率.

结论:

在TAVI之前减少LVSWI与AS患者的治疗结果较差有关.
结合LV SWI和GLS评估可能会提高TAVI治疗AS患者的预后风险分层.

关键词:

大动脉狭窄症心声检查预后情况一次性创伤

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