在患有心脏植入式电子器件的患者中进行跨管跨管替换
Kent Chak-Yu So1, Lukas Stolz2, Neil Fam3
1Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong Special Administration Region, China.
JACC. Asia
|August 30, 2025
概括
对于心脏植入式电子器件 (CIED) 的患者来说,通过导管三门置换 (TTVR) 是安全有效的. 这项研究显示CIED和非CIED组的结果相似,支持该群体的TTVR.
科学领域:
- 心脏病学
- 干预心脏病学
- 心脏外科
背景情况:
- 心脏植入式电子器件 (CIED) 常常会出现三管吐.
- 过导管三门置换 (TTVR) 对于患有CIED的患者来说是一个可行的选择,但数据有限.
研究的目的:
- 评估使用LuX- Valve Plus在有症状的TR和CIED患者中的跨TTVR的安全性和有效性.
- 为了比较接受TTVR的CIED和无CIED患者之间的结果.
主要方法:
- 在2022年1月至2024年8月期间,对99名患者进行同情性使用的横TTVR (LuX-Valve Plus) 的回顾性分析.
- 治疗成功,TR降低,30天死亡率,功能类别和CIED功能的比较.
主要成果:
- 在CIED和非CIED组中,手术成功率 (91. 7% vs 95. 2%),30天死亡率 (5. 6% vs 4. 8%) 和TR降低率 (83. 8% vs 84. 9%) 是可比的.
- 虽然CIED组的转化为手术和重新干预的数值发生率较高,但这些都没有达到统计学意义.
- 在大多数患者中,术后CIED功能保持稳定,在参数恶化患者中不需要替代或提取.
结论:
- 通过的TTVR是一种安全有效的治疗TR和心力衰竭的患者.
- 需要进行更大规模的前性研究来证实这些发现,并验证该特定患者群体的结果.
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